Details for gene set HUMANCYC_GLYCINE BETAINE DEGRADATION[GSEA]

Table: GSEA Results Summary

Dataset	Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos
Phenotype	phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos
Upregulated in class	truncNotch
GeneSet	HUMANCYC_GLYCINE BETAINE DEGRADATION
Enrichment Score (ES)	-0.78377545
Normalized Enrichment Score (NES)	-1.4392465
Nominal p-value	0.039855074
FDR q-value	0.5750998
FWER p-Value	1.0

Fig 1: Enrichment plot: HUMANCYC_GLYCINE BETAINE DEGRADATION
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	SARDH	3060044	4440	0.106	-0.2031	No
2	SDSL	6900435	4561	0.098	-0.1767	No
3	PIPOX	70750	7806	0.002	-0.3506	No
4	BHMT	6660138	8696	-0.013	-0.3939	No
5	BHMT2	2030184	9164	-0.021	-0.4120	No
6	DMGDH	3830601	9514	-0.027	-0.4217	No
7	SDS	110242 6380725	9540	-0.027	-0.4139	No
8	ST6GALNAC2	2680402	12449	-0.111	-0.5332	Yes
9	SHMT1	5900132	17112	-1.264	-0.3608	Yes
10	SHMT2	1850180 6040010	17179	-1.320	0.0772	Yes

Fig 3: HUMANCYC_GLYCINE BETAINE DEGRADATION: Random ES distribution
Gene set null distribution of ES for HUMANCYC_GLYCINE BETAINE DEGRADATION